Title of article
Serotonergic and dopaminergic activities of rigidified (R)-aporphine derivatives
Author/Authors
Tero Linnanen، نويسنده , , Magnus Brisander، نويسنده , , Nina Mohell، نويسنده , , Anette M. Johansson، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2001
Pages
4
From page
367
To page
370
Abstract
Novel rigidified (R)-aporphine derivatives were synthesized from (R)-1,11-carbonylaporphine by ring expansion reactions. The structures of the novel analogues were assigned by NMR spectroscopy and X-ray crystallography. The compounds showed moderate affinities and selectivities at serotonin 5-HT1A and 5-HT7 and dopamine D2A receptors.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2001
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
800348
Link To Document