Author/Authors :
Sheila Srinivasan، نويسنده , , Christopher McGuigan، نويسنده , , Graciela Andrei، نويسنده , , Robert Snoeck، نويسنده , , Erik De Clercq، نويسنده , , Jan Balzarini، نويسنده ,
Abstract :
Novel bicyclic nucleoside analogues bearing long alkyl side chains are prepared and tested as inhibitors of VZV. In particular, analogues with terminal unsaturation in the side chain are reported. Whilst terminal alkenyl derivatives are potent antivirals, the corresponding terminal alkynyls are poorly active.
