Title of article
Identification and characterization of a potential ischemia-selective N-methyl- -aspartate (NMDA) receptor ion-channel blocker, CNS 5788
Author/Authors
Seetharamaiyer Padmanabhan، نويسنده , , Michael E. Perlman، نويسنده , , Lu Zhang، نويسنده , , Deke Moore، نويسنده , , Dan Zhou، نويسنده , , James B. Fischer، نويسنده , , Graham J. Durant، نويسنده , , Robert N. McBurney، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2001
Pages
4
From page
501
To page
504
Abstract
The identification and characterization of a potentially ischemia-selective and orally-active sulfoxide based NMDA ion-channel blocker showing good neuroprotective activity, (R)-(+)-N-(2-chloro-5-methylthiophenyl)-N′-(3-methylsulfinylphenyl)-N′-methylguanidine (CNS 5788), is described.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2001
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
800381
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