Author/Authors :
Falguni Dasgupta، نويسنده , , N. Gangadhar، نويسنده , , M. Bruhaspathy، نويسنده , , Ashwani K. Verma، نويسنده , , Simi Sarin، نويسنده , , Ashish K. Mukherjee، نويسنده ,
Abstract :
A series of new peptoids as endothelin receptor antagonists has been synthesized. Screening them for their ability to bind with endothelin receptors (ETA and ETB) competitively in the presence of (125I) endothelin led to the discovery of compounds as possible leads with IC50s in the low micromolar concentrations.
