Suppression of life-threatening tachyarrhyhmias, and atrio-ventricular ischemic block following the administration of anti-inflammatory intravenous drug

The occurrence of potentially lethal tachyarrhyhmias, or severe bradyarrhytmias could be the end of a cascade of pathophysiological abnormalities. These arrhythmias, occurring in the presence of a decompensated cardiopathy, can be inferred to have an inflammatory etiology. In the present study, we found that administration of an anti-inflammatory compound (ibuprofen IV) during the electrical storm resulted in an immediate suppression of the threatening arrhythmias.