Preparing of a New Herbal Medicine Formulation for Minor Aphthous Ulcers

Recurrent Aphthous Stomatitis (RAS) is one of the most common problems recognized by dentists and skin specialists. This problem is characterized by recurring, painful, small oral mucosal ulcers with a round or oval aspect which mostly appear in keratinized mucosa, cheeks and on the surface of mouth under the tongue. The aim of this study was to determine the effect of a new herbal medicine on minor RAS as a treatment, which is more effective and has fewer side effects. The study was carried out by Double-Blind method. The extract of medical plants Mellisa officinalis, Myrtus communis and Quercus robur were used in the form of liquid. Statistical analysis on recovery of lesions irritation in groups A, B, C, D and E at different time intervals showed that the participants in group C experienced the most irritation decrease compared to other groups at times 72, 96 and 120 hours.