Title of article :
COGNITIVE IMPAIRMENT AND LOW PHYSICAL ACTIVITY
ARE THE COMPONENTS OF FRAILTY MORE STRONGLY ASSOCIATED
WITH DISABILITY
Author/Authors :
J.A. ?vilA-Funes1، نويسنده , , 2، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2011
Abstract :
to determine the association of the five frailty criteria from the cardiovascular Health
study, as well as cognitive impairment, with prevalent disability for the instrumental (iADl) and basic activities
of daily living (ADl). Design: cross-sectional study of 475 community-dwelling subjects aged 70 and older,
participating in the Mexican study of nutritional and Psychosocial Markers of Frailty. Measurements: six
probable frailty criteria were considered: weight loss, poor endurance, low physical activity, slowness, weakness,
and cognitive impairment. the association of each component of frailty for iADl and ADl disability as main
outcomes was determined constructing multivariate logistic regression analyses. Final models were adjusted by
socio-demographic factors and the presence of the other five frailty components as covariates. Results: Mean age
of participants was 78.1 (sD=6.2). the unadjusted results showed that each of the components of frailty, except
weight loss, was associated with both iADl and ADl disability. However, after adjustment, only low physical
activity [odds ratio (or) =3.27; 95% ci=1.56 to 6.85] and cognitive impairment (or=2.06; 95% ci=1.04 to
4.06) remain independently associated with iADl disability. regarding ADl disability, only a lower physical
activity (or=7.72; 95% ci=1.28 to 46.46) was associated with this outcome, whereas cognitive impairment was
marginally associated but was not statistically significant (or=5.45; 95% ci=0.91 to 32.57). Conclusions:
cognitive impairment and low physical activity are the main contributing factors of frailty phenotype to
disability. better understanding the independent contribution of each frailty subdimension to the different
adverse-health outcomes may help to provide a more adequate management of frail elderly
Keywords :
Physical activity , Disability , Frailty , Cognitive impairment
Journal title :
The journal of nutrition, health & aging
Journal title :
The journal of nutrition, health & aging