Title of article :
Travelling waves in a wound healing assay
Original Research Article
Author/Authors :
P.K. Maini، نويسنده , , DLS McElwain، نويسنده , , D Leavesley، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2004
Abstract :
Several authors have predicted that cell propagation in a number of biological contexts, for example, wound healing, tumour cell invasion, angiogenesis etc., occurs due to a constant speed travelling wave of invasion. The analyses of these models to arrive at this prediction is, in many cases, essentially an extension of the classical analysis of Fisherʹs equation. Here, we show that a very simple wound healing assay does indeed give rise to constant speed travelling waves. To our knowledge, this is the first verification of Fisherʹs equation in a medical context.
Keywords :
Fisherיs equation , Invasion waves , Human peritoneal mesothelial cells
Journal title :
Applied Mathematics Letters
Journal title :
Applied Mathematics Letters