Title of article
The Gompertzian curve reveals fractal properties of tumor growth
Author/Authors
Przemyslaw Waliszewski، نويسنده , , Jerzy Konarski، نويسنده ,
Issue Information
دوهفته نامه با شماره پیاپی سال 2003
Pages
10
From page
665
To page
674
Abstract
The normalized Gompertzian curve reflecting growth of experimental malignant tumors in time can be fitted by the power function y(t)=atb with the coefficient of nonlinear regression r 0.95, in which the exponent b is a temporal fractal dimension, (i.e., a real number), and time t is a scalar. This curve is a fractal, (i.e., fractal dimension b exists, it changes along the time scale, the Gompertzian function is a contractable mapping of the Banach space R of the real numbers, holds the Banach theorem about the fix point, and its derivative is 1). This denotes that not only space occupied by the interacting cancer cells, but also local, intrasystemic time, in which tumor growth occurs, possesses fractal structure. The value of the mean temporal fractal dimension decreases along the curve approaching eventually integer values; a fact consistent with our hypothesis that the fractal structure is lost during tumor progression.
Journal title
Chaos, Solitons and Fractals
Serial Year
2003
Journal title
Chaos, Solitons and Fractals
Record number
900289
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