Author/Authors :
Kim، Jong-Joo نويسنده , , Georges، Michel نويسنده , , Blott، Sarah نويسنده , , Moisio، Sirja نويسنده , , Schmidt-Kuntzel، Anne نويسنده , , Cornet، Anne نويسنده , , Berzi، Paulette نويسنده , , Cambisano، Nadine نويسنده , , Ford، Christine نويسنده , , Grisart، Bernard نويسنده , , Johnson، Dave نويسنده , , Karim، Latifa نويسنده , , Simon، Patricia نويسنده , , Snell، Russell نويسنده , , Spelman، Richard نويسنده , , Wong، Jerry نويسنده , , Vilkki، Johanna نويسنده , , Farnir، Frederic نويسنده , , Coppieters، Wouter نويسنده ,
Abstract :
We herein report on our efforts to improve the mapping resolution of a QTL with major effect on milk yield and composition that was previously mapped to bovine chromosome 20. By using a denser chromosome 20 marker map and by exploiting linkage disequilibrium using two distinct approaches, we provide strong evidence that a chromosome segment including the gene coding for the growth hormone receptor accounts for at least part of the chromosome 20 QTL effect. By sequencing individuals with known QTL genotype, we identify an F to Y substitution in the transmembrane domain of the growth hormone receptor gene that is associated with a strong effect on milk yield and composition in the general population.
Keywords :
Pine barrens , N deposition , Ectomycorrhizae , Indicator species , Oligotrophic soils
