A model independent determination of |Vub|

It is shown that measuring the lepton invariant mass spectrum in inclusive semileptonic B̄→Xuℓν̄ decay yields a model independent determination of |Vub|. Unlike the lepton energy and hadronic invariant mass spectra, nonperturbative effects are only important in the resonance region, and play a parametrically suppressed role when dΓ/dq2 is integrated over q2>(mB−mD)2, which is required to eliminate the charm background. Perturbative and nonperturbative corrections are presented to order αs2β0 and ΛQCD2/mb2, and the ΛQCD3/mb3 corrections are used to estimate the uncertainty in our results. The utility of the B̄→Xsℓ+ℓ− decay rate above the ψ(2S) resonance is discussed.