Title of article
Evaluation of some DNA cloning strategies
Author/Authors
B. Tang، نويسنده ,
Issue Information
دوهفته نامه با شماره پیاپی سال 2000
Pages
6
From page
43
To page
48
Abstract
By considering a DNA molecule as a random sequence of four letters, a mathematical model of two important steps in DNA cloning processes is described: degradation of large DNA molecules using restriction enzymes, and replication of the resulting DNA fragments by viral vectors. The model is used to evaluate the feasibility of obtaining target gene loci using a large number of restriction enzymes, and to estimate the fraction of genomic DNA that is clonable.
Journal title
Computers and Mathematics with Applications
Serial Year
2000
Journal title
Computers and Mathematics with Applications
Record number
918997
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