Author/Authors :
Boloursaz، Mohammad-Reza نويسنده , , Khalilzadeh، Soheila نويسنده , , Rahmati nezhad، Pegah نويسنده Pediatric Respiratory Diseases Research Center, NRITLD, Masih Daneshvari Hospital, Shahid Beheshti University of Medical Sciences, Tehran , Iran , , Bakhshayesh Karam، Mehrdad نويسنده , , Mahdaviani، Alireza نويسنده Pediatric Respiratory Diseases Research Center, NRITLD, Masih Daneshvari Hospital, Shahid Beheshti University of Medical Sciences, Tehran , Iran , , Mosadegh، Leila نويسنده Department of Radiology, Chronic Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shah Mosadegh, Leila , Hassanzad، Maryam نويسنده , , Mir Hosseini، Seyed Mohsen نويسنده Chronic Respiratory Disease Research Center, NRITLD, Shahid Beheshti University M.C., TEHRAN-IRAN. ,
Abstract :
Background: This study aimed at evaluating HRCT pulmonary manifestations
in children with Common Variable Immunodeficiency (CVID) hospitalized in
the Pediatric Ward of Masih Daneshvari Hospital during a 10-year period.
Materials and Methods: This retrospective study evaluated 25 children
hospitalized with the diagnosis of CVID in the Pediatric Ward of Masih
Daneshvari Hospital from 2001 to 2011 and their pulmonary HRCT scans were
evaluated.
Results: The most common pulmonary HRCT findings were lymphadenopathy
(66.7%), bronchiectasis (50%), air trapping (33.3%) and peribronchial wall
thickening (33.3%). The highest percentage of CT-scan findings was detected in
patients aged 13-17 yrs.
Conclusion: Most of the pulmonary changes due to CVID are preventable or
treatable. Also, it is possible to prevent irreversible complications of disease if it
is diagnosed early. Therefore, HRCT is strongly recommended as an accurate
and effective method for monitoring and fast recognition of pulmonary
manifestations of the disease especially bronchiectasis which is a very common
finding indicative of poor prognosis.
