One-pot synthesis of 1,2-O-isopropylidene-α-d-xylofuranose

The title compound 1 was prepared by sulfuric acid-catalyzed acetalation of d-xylose followed by partial hydrolysis with aqueous sodium carbonate added directly to a crude acetalation mixture. The yield of crystalline 1 (mp 42–43°C) was 80%.