• Title of article

    Synthesis of methyl 4-thio-β-cellobioside. A reinvestigation

  • Author/Authors

    Vincent Moreau، نويسنده , , Jens Chr. Norrild، نويسنده , , Hugues Driguez، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 1997
  • Pages
    7
  • From page
    271
  • To page
    277
  • Abstract
    The best yield for the synthesis of the title compound was obtained by nucleophilic displacement of the 4-O-triflyl group in methyl tri-O-benzyl-4-O-triflyl-β-d-galactopyranoside by 2,3,4,6-tetra-O-acetyl-1-S-acetyl-1-thio-β-d-glucopyranose in HMPA in the presence of diethylamine. Under these conditions, the formation of unsaturated side products was decreased.
  • Keywords
    Thioglycosides , Methyl 4-thio-?-cellobioside , E2-Elimination , SN2 substitution
  • Journal title
    Carbohydrate Research
  • Serial Year
    1997
  • Journal title
    Carbohydrate Research
  • Record number

    961781