Synthesis, separation and NMR spectral analysis of methyl apiofuranosides

Methyl apiofuranosides were prepared by methanolysis of d-apiose. Four methyl apiofuranosides were separated by ion-exclusion and normal phase chromatography and their structures were characterized by 1H and 13C NMR spectroscopy. The composition of methyl apiofuranosides was almost the same as that of d-apiose in D2O.