Title of article
Cholesteryl-cyclodextrins: synthesis and insertion into phospholipid membranes
Author/Authors
Rachel Auzély-Velty، نويسنده , , Bruno Perly، نويسنده , , Olivier Taché، نويسنده , , Thomas Zemb، نويسنده , , Philippe Jéhan، نويسنده , , Pierre Guenot، نويسنده , , Jean-Pierre Dalbiez، نويسنده , , Florence Djeda??ni-Pilard، نويسنده ,
Issue Information
دوهفته نامه با شماره پیاپی سال 1999
Pages
9
From page
82
To page
90
Abstract
6I-(Cholest-5-en-3β-yloxycarbonyl)amino-6I-deoxycyclomaltoheptaose and 6I-(cholest-5-en-3α-ylamido)succinylamido-6I-deoxycyclomaltoheptaose were synthesized and fully characterized by NMR spectroscopy experiments and mass spectrometry analysis. Incorporation of these monosubstituted amphiphilic cyclodextrins into phospholipid bilayers was investigated using small-angle X-ray scattering, differential scanning calorimetry and 31P nuclear magnetic resonance. Different modes of incorporation depending on the spacer length between the cyclodextrin and cholesterol moieties were observed.
Keywords
Phospholipid bilayers , Amphiphilic cyclodextrins , NMR spectroscopy , X-ray scattering
Journal title
Carbohydrate Research
Serial Year
1999
Journal title
Carbohydrate Research
Record number
962348
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