Syntheses of the l-manno and some other analogs of the terminal determinants of the O-PS of Vibrio cholerae O:1 Original Research Article

Analogs of the methyl α-glycosides of the terminal residues of the O-specific polysaccharides (O-PS) of Vibrio cholerae O:1, serotype Inaba and Ogawa, have been prepared as probes to study their interaction with anti V. cholerae O:1 antibodies. They differ from the termini of the respective O-PSs in anomeric or absolute configuration of perosamine, position of the O-methyl group in d-perosamine, and nature of the N-acyl side chain.