Chondroitin O-methyl ester: an unusual substrate for chondroitin AC lyase Original Research Article

Chondroitin O-methyl ester was depolymerized by chondroitin AC lyase (EC 4.2.2.5) from Flavobacterium heparinum. The major product isolated from the depolymerization reaction was found to be methyl α-l-threo-hex-4-enopyranosyluronate-(1→4)-2-acetamido-2-deoxy-α,β-d-galactopyranoside.