Title of article
Synthesis of mannopyranose disaccharides as photoaffinity probes for mannosyltransferases in Mycobacterium tuberculosis Original Research Article
Author/Authors
Ashish K. Pathak، نويسنده , , Vibha Pathak، نويسنده , , James R. Riordan، نويسنده , , Sudagar S. Gurcha، نويسنده , , Gurdyal S Besra، نويسنده , , Robert C Reynolds، نويسنده ,
Issue Information
دوهفته نامه با شماره پیاپی سال 2004
Pages
9
From page
683
To page
691
Abstract
Mannosyltransferases play a crucial role in mycobacterial cell-wall biosynthesis and are potential new drug targets for the treatment of tuberculosis. Herein, we describe the synthesis of α-(1 → 2)- and α-(1 → 6)-linked mannopyranosyl disaccharides possessing a 5-azidonaphthlene-1-sulfonamidoethyl group as photoaffinity probes for active-site labeling studies of mannosyltransferases in Mycobacetrium tuberculosis.
Keywords
Disaccharide , Photoaffinity probe , Mannosyltransferases , Mycobacterium tuberculosis , Mannose
Journal title
Carbohydrate Research
Serial Year
2004
Journal title
Carbohydrate Research
Record number
964011
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