Synthesis of N-sugar-substituted phthalimides and their derivatives from sugar azides and phthalic anhydride Original Research Article

N-Sugar-substituted phthalimides and tetrachlorophthalimide derivatives can be prepared in good yields under essentially neutral conditions. Mixing a sugar azide, NaI, Me3SiCl, phthalic or substituted phthalic anhydride and tetrabutylammonium iodide as catalyst in acetonitrile at rt or 60 °C, afforded 12 imides in 83–95% yields.