Synthesis of a hexasaccharide fragment of group E streptococci polysaccharide and the tetrasaccharide repeating unit of E. coli O7:K98:H6 Original Research Article

Syntheses of a hexasaccharide, the dimer of the repeating unit of the group E streptococci polysaccharide, and a tetrasaccharide, the repeating unit of the E. coli O7:K98:H6, were achieved by constructing alternate α-l-(1 → 2)- and α-l-(1 → 3)-linked l-rhamnopyranose backbones and substituting with β-linked d-glucopyranose side chains for the former, and a d-glucopyranosyluronate branch for the latter, respectively, at O-2 of the l-rhamnose ring.