Title of article
The chemistry of castanospermine. Direct oxidation of the tetraacetate to the corresponding γ-lactam Original Research Article
Author/Authors
Richard H. Furneaux، نويسنده , , Graeme J Gainsford، نويسنده , , Jennifer M. Mason، نويسنده , , Peter C. Tyler، نويسنده ,
Issue Information
دوهفته نامه با شماره پیاپی سال 2004
Pages
5
From page
1747
To page
1751
Abstract
From the products of oxidation of tetra-O-acetylcastanospermine (2) with N-bromosuccinimide, only the γ-lactam 11 was isolated (19%). Treatment of this lactam with DBU in dichloromethane afforded the elimination product 12, while deacetylation with sodium methoxide in methanol gave tetraol 13 together with diene 14. The X-ray crystal structure of compound 13 is reported.
Keywords
Castanospermine , Oxidation , Lactam
Journal title
Carbohydrate Research
Serial Year
2004
Journal title
Carbohydrate Research
Record number
964146
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