Title of article
Synthesis of a C3-symmetric (1→6)-N-acetyl-β-d-glucosamine octadecasaccharide using click chemistry Original Research Article
Author/Authors
Qi Chen، نويسنده , , Feng Yang، نويسنده , , Yuguo Du، نويسنده ,
Issue Information
دوهفته نامه با شماره پیاپی سال 2005
Pages
7
From page
2476
To page
2482
Abstract
A C3-symmetric (1→6)-N-acetyl-β-d-glucosamine octadecasaccharide was convergently synthesized on the basis of a copper(I)-catalyzed 1,3-dipolar cycloaddition reaction of azide and alkyne. The target octadecasaccharide showed good antitumor activity against H22 in the preliminary mice tests.
Keywords
Glycosylation , Click chemistry , Glucosamine , Antitumor activity , Thioglycosides
Journal title
Carbohydrate Research
Serial Year
2005
Journal title
Carbohydrate Research
Record number
964563
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