Title of article :
Use of methanesulfonic acid in the reductive ring-opening of O-benzylidene acetals
Author/Authors :
Alexander I. Zinin، نويسنده , , Nelly N. Malysheva، نويسنده , , Anna M. Shpirt، نويسنده , , Vladimir I. Torgov، نويسنده , , Leonid O. Kononov، نويسنده ,
Issue Information :
دوهفته نامه با شماره پیاپی سال 2007
Abstract :
Methanesulfonic acid was shown to be an efficient and convenient substitute for ethereal HCl in reductive 4,6-O-benzylidene acetal ring-opening reaction with sodium cyanoborohydride in THF. Normal regioselectivity was observed, the 6-O-benzyl ethers with free 4-OH group being the major products of the reaction.
Keywords :
Methanesulfonic acid , Sodium cyanoborohydride , Reduction , Benzylidene acetal , Regioselectivity
Journal title :
Carbohydrate Research
Journal title :
Carbohydrate Research
