Title of article
First round of a focused library of cholera toxin inhibitors Original Research Article
Author/Authors
Crtomir Podlipnik، نويسنده , , Ingrid Velter، نويسنده , , Barbara La Ferla، نويسنده , , Gilles Marcou، نويسنده , , Laura Belvisi، نويسنده , , Francesco Nicotra، نويسنده , , Anna Bernardi، نويسنده ,
Issue Information
دوهفته نامه با شماره پیاپی سال 2007
Pages
10
From page
1651
To page
1660
Abstract
C-Galactosides have been used as scaffolds to design a library of non-hydrolysable inhibitors of cholera toxin (CT). Test elements from the library were synthesized and found to inhibit CT binding to an asialofetuin-coated SPR chip with micromolar affinity. Preliminary results are reported.
Keywords
cholera toxin , Glycomimetics , Carbohydrate mimics , GM1 ganglioside , C-Glycosides
Journal title
Carbohydrate Research
Serial Year
2007
Journal title
Carbohydrate Research
Record number
964778
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