Synthesis and biological evaluation of a small library of nojirimycin-derived bicyclic iminosugars Original Research Article

Novel nojirimycin-derived bicyclic structures, containing cyclic carbamate, urea and guanidine moieties have been synthesised starting from suitably protected α-C-vinylnojirimycin and α-C-allylnojirimycin, respectively, and their biological activity against different glycosidases and as antibacterial agents tested.