Synthesis of N- and S-bis-protected lactosyl isothiobiurets

Several N,S-bis(hepta-O-acetyllactosyl)-1-aryl-2-isothiobiuret compounds have been synthesised for the first time by the reaction of S-(hepta-O-acetyl-β-lactosyl)-1-arylisothiocarbamides and hepta-O-acetyl-β-lactosyl isocyanate. The identities of these newly synthesised compounds were established on the basis of elemental analysis and IR, 1H NMR, 13C NMR and mass spectral studies.