Title of article :
Synthesis of 1-d-6-O-[2-(N-hydroxyaminocarbonyl)amino-2-deoxy-α-d-glucopyranosyl]-myo-inositol 1-(n-octadecyl phosphate): a potential metalloenzyme inhibitor of glycosylphosphatidylinositol biosynthesis
Author/Authors :
Arthur T. Crossman، نويسنده , , Michael D. Urbaniak، نويسنده , , Michael A.J. Ferguson، نويسنده ,
Issue Information :
دوهفته نامه با شماره پیاپی سال 2008
Abstract :
1-d-6-O-[2-(N-Hydroxyaminocarbonyl)amino-2-deoxy-α-d-glucopyranosyl]-myo-inositol 1-(n-octadecyl phosphate) was prepared to probe the reaction mechanism of the putative zinc-dependent metalloenzyme 2-acetamido-2-deoxy-α-d-glucopyranosyl-(1→6)-phosphatidylinositol de-N-acetylase of glycosylphosphatidylinositol biosynthesis.
Keywords :
Glycosylphosphatidylinositol (GPI) membrane anchors , N-Hydroxyurea , N-Acetyl-d-glucosaminylphosphatidylinositol de-N-acetylase , Zinc metalloenzyme inhibitor
Journal title :
Carbohydrate Research
Journal title :
Carbohydrate Research
