• Title of article

    Synthesis of 1-d-6-O-[2-(N-hydroxyaminocarbonyl)amino-2-deoxy-α-d-glucopyranosyl]-myo-inositol 1-(n-octadecyl phosphate): a potential metalloenzyme inhibitor of glycosylphosphatidylinositol biosynthesis

  • Author/Authors

    Arthur T. Crossman، نويسنده , , Michael D. Urbaniak، نويسنده , , Michael A.J. Ferguson، نويسنده ,

  • Issue Information
    دوهفته نامه با شماره پیاپی سال 2008
  • Pages
    4
  • From page
    1478
  • To page
    1481
  • Abstract
    1-d-6-O-[2-(N-Hydroxyaminocarbonyl)amino-2-deoxy-α-d-glucopyranosyl]-myo-inositol 1-(n-octadecyl phosphate) was prepared to probe the reaction mechanism of the putative zinc-dependent metalloenzyme 2-acetamido-2-deoxy-α-d-glucopyranosyl-(1→6)-phosphatidylinositol de-N-acetylase of glycosylphosphatidylinositol biosynthesis.
  • Keywords
    Glycosylphosphatidylinositol (GPI) membrane anchors , N-Hydroxyurea , N-Acetyl-d-glucosaminylphosphatidylinositol de-N-acetylase , Zinc metalloenzyme inhibitor
  • Journal title
    Carbohydrate Research
  • Serial Year
    2008
  • Journal title
    Carbohydrate Research
  • Record number

    965503