Title of article
Deprotonation of β-cyclodextrin in alkaline solutions
Author/Authors
Ernestas Gaidamauskas، نويسنده , , Eugenijus Norkus، نويسنده , , Eugenijus Butkus، نويسنده , , Debbie C. Crans، نويسنده , , Giedr? Grincien?، نويسنده ,
Issue Information
دوهفته نامه با شماره پیاپی سال 2009
Pages
5
From page
250
To page
254
Abstract
Variable pH 13C NMR and 1H NMR spectroscopic studies of the β-cyclodextrin (β-CD) in alkaline aqueous solutions revealed that β-CD does not deprotonate at pH < 12.0. Further increase in solution pH results in the deprotonation of OH-groups adjacent to C-2 and C-3 carbon atoms of β-CD glucopyranose units, whereas the deprotonation of OH-groups adjacent to C-6 carbon atoms is expressed less markedly. The pKa values for β-CD OH-groups adjacent to C-2 and C-3 carbon atoms are rather close, pKa1,2 being 13.5 ± 0.2 (22.5 °C).
Keywords
Deprotonation , ?-Cyclodextrin , pKa , 13C NMR , 1H NMR
Journal title
Carbohydrate Research
Serial Year
2009
Journal title
Carbohydrate Research
Record number
965706
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