Author/Authors :
Claire-Marie Thomas، نويسنده , , Diego Montenegro، نويسنده , , Alejandra Casta?o، نويسنده , , Laura Friedman، نويسنده , , Jay Leb، نويسنده , , Mia Lace Huang، نويسنده , , Leah Rothman، نويسنده , , Heidi Lee، نويسنده , , Craig Capodiferro، نويسنده , , Daniel Ambinder، نويسنده , , Eva Cere، نويسنده , , Jessica Galante، نويسنده , , JaimeLee Rizzo، نويسنده , , Karin Melkonian، نويسنده , , Robert Engel، نويسنده ,
Abstract :
In our continuing investigation of polycationic salts for purposes of antimicrobial action, ion-channel blocking, and construction of ionic liquids, we have prepared several series of polycationic salts derived from carbohydrate precursors. These salts are currently being investigated for optimal efficacy as antibacterials and antifungals, as well as for other applications. The syntheses of such series of salts are described here along with preliminary antibacterial testing results and a discussion of their properties indicating their potential utility for several purposes.
Keywords :
Salts , Antibacterial , Cationic carbohydrates , Lipids , Alditol derivatives
