Title of article
Total synthesis of caminoside B, a novel antimicrobial glycolipid isolated from the marine sponge Caminus sphaeroconia Original Research Article
Author/Authors
Zaihong Zhang، نويسنده , , Chengli Zong، نويسنده , , Gaopeng Song، نويسنده , , Guokai Lv، نويسنده , , Yuexing Chun، نويسنده , , Peng Wang، نويسنده , , Chuan-Ning Ding، نويسنده , , Yingxia Li، نويسنده ,
Issue Information
دوهفته نامه با شماره پیاپی سال 2010
Pages
11
From page
750
To page
760
Abstract
The first total synthesis of caminoside B, a novel marine antimicrobial glycolipid isolated from the marine sponge Caminus sphaeroconia, was developed. This marine small molecule inhibitor (IC50 = 20 μM) targeting type III secretory pathway of bacterial pathogenesis was assembled in good yield via a ‘2+2+1’ strategy based on stereocontrolled construction of the four glycosidic linkages.
Keywords
Regioselective glycosylation , Caminoside B , Antimicrobial glycolipid , Type III secretory pathway
Journal title
Carbohydrate Research
Serial Year
2010
Journal title
Carbohydrate Research
Record number
966935
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