Title of article
Structural and genetic characterization of the O-antigen of Salmonella enterica O56 containing a novel derivative of 4-amino-4,6-dideoxy-d-glucose Original Research Article
Author/Authors
Andrei V. Perepelov، نويسنده , , Bin Liu، نويسنده , , Sergei D. Shevelev، نويسنده , , Sof’ya N. Senchenkova، نويسنده , , Bo Hu، نويسنده , , Alexander S. Shashkov، نويسنده , , Lu Feng، نويسنده , , Yuriy A. Knirel، نويسنده , , Lei Wang، نويسنده ,
Issue Information
دوهفته نامه با شماره پیاپی سال 2010
Pages
5
From page
1891
To page
1895
Abstract
Based on the O-antigens (O-polysaccharides), one of the most variable cell constituents, 46 O-serogroups have been recognized in the Kauffmann–White serotyping scheme for Salmonella enterica. In this work, the structure of the O-polysaccharide and the genetic organization of the O-antigen gene cluster of S. enterica O56 were investigated. As judged by sugar and methylation analyses, along with NMR spectroscopic data, the O-polysaccharide has a linear tetrasaccharide O-unit, which consists of one residue each of d-ribofuranose, N-acetyl-d-glucosamine, N-acetyl-d-galactosamine, and a novel sugar derivative, 4-(N-acetyl-l-seryl)amino-4,6-dideoxy-d-glucose (d-Qui4NSerAc). The following structure of the O-polysaccharide was established:
Keywords
4-Amino-4 , Bacterial polysaccharide structure , Salmonella enterica , O-antigen , O-Antigen gene cluster , 6-dideoxy-d-glucose
Journal title
Carbohydrate Research
Serial Year
2010
Journal title
Carbohydrate Research
Record number
967091
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