Title of article
A highly efficient deprotection of the 2,2,2-trichloroethyl group at the anomeric oxygen of carbohydrates
Author/Authors
Jianbo Zhang، نويسنده , , Jie Fu، نويسنده , , Wenshuai Si، نويسنده , , Xiaohu Wang، نويسنده , , Zhongfu Wang، نويسنده , , Jie Tang، نويسنده ,
Issue Information
دوهفته نامه با شماره پیاپی سال 2011
Pages
4
From page
2290
To page
2293
Abstract
Commercially available zinc dust in the presence of ammonium chloride in acetonitrile at reflux removes the 2,2,2-trichloroethyl (TCE) group at anomeric centers with excellent yields (>95%) in short reaction times. This present method is easily implemented on substrates containing acyl and benzyl groups and large-scale reactions also proceed in high yield.
Keywords
2 , 2 , 2-Trichloroethyl , Carbohydrates , Zinc dust , Deprotection , Anomeric center
Journal title
Carbohydrate Research
Serial Year
2011
Journal title
Carbohydrate Research
Record number
967318
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