Title of article
Glycosylation of α-amino acids by sugar acetate donors with InBr3. Minimally competent Lewis acids
Author/Authors
Mark R. Lefever، نويسنده , , Lajos Z. Szab?، نويسنده , , Bobbi Anglin، نويسنده , , Michael Ferracane، نويسنده , , Joanna Hogan، نويسنده , , Lauren Cooney، نويسنده , , Robin Polt، نويسنده ,
Issue Information
دوهفته نامه با شماره پیاپی سال 2012
Pages
5
From page
121
To page
125
Abstract
A simplified method for the preparation of Fmoc-serine and Fmoc-threonine glycosides for use in O-linked glycopeptide synthesis is described. Lewis acids promote glycoside formation, but also promote undesired reactions of the glycoside products. Use of ‘minimally competent’ Lewis acids such as InBr3 promotes the desired activation catalytically, and with greatly reduced side products from sugar peracetates.
Keywords
O-linked glycopeptides , Threonine , Serine , Indium tribromide , Glycosylation
Journal title
Carbohydrate Research
Serial Year
2012
Journal title
Carbohydrate Research
Record number
967505
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