Author/Authors :
Naoko Takeda، نويسنده , , Remina Ikeda-Matsumi، نويسنده , , Kaoru Ebara-Nagahara، نويسنده , , Miyuki Otaki-Nanjo، نويسنده , , Kayo Taniguchi-Morita، نويسنده , , Miwa Nanjo، نويسنده , , Jun-ichi Tamura، نويسنده ,
Abstract :
Regiospecifically sulfated heparan sulfate tetrasaccharide, GlcAβ-GlcN(NS6S)α-GlcAβ-GlcN(NS6S)α was first synthesized as an octyl glycoside. Total synthesis was achieved effectively by coupling the corresponding disaccharide units in short steps.
Keywords :
Oligosaccharide , Glycosaminoglycan , Heparan sulfate , Heparanase