Title of article
Facile total synthesis of (−)-(5R,6S)-6-acetoxy-5-hexadecanolide from carbohydrate, a mosquito oviposition attractant pheromone Original Research Article
Author/Authors
Saibal Das، نويسنده , , Anand Kumar Mishra، نويسنده , , Ashish Kumar، نويسنده , , Ahamad Al Khazim Al Ghamdi، نويسنده , , Jhillu Singh Yadav، نويسنده ,
Issue Information
دوهفته نامه با شماره پیاپی سال 2012
Pages
5
From page
7
To page
11
Abstract
Total synthesis of (−)-(5R,6S)-6-acetoxy-5-hexadecanolide, a major component of mosquito oviposition attractant pheromones is reported. The key synthetic steps involve epoxide opening by lithiated salt of ethylpropionate and acid catalysed lactonization. The total synthesis was achieved in 11 linear steps staring from a readily available carbohydrate δ-gluconolactone in 18% overall yield making it simple, practical and elegant.
Keywords
Carbohydrate , Hydrazone , Pheromone , Total synthesis , Lactone
Journal title
Carbohydrate Research
Serial Year
2012
Journal title
Carbohydrate Research
Record number
967669
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