• Title of article

    Detection of the marine toxin okadaic acid in mussels during a diarrhetic shellfish poisoning (DSP) episode in Thermaikos Gulf, Greece, using biological, chemical and immunological methods

  • Author/Authors

    Theoni Mouratidou a، نويسنده , , b، نويسنده , , *، نويسنده , , Ignatia Kaniou-Grigoriadou a، نويسنده , , Constantini Samarab، نويسنده , , Themistokles Kouimtzis b، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2006
  • Pages
    11
  • From page
    894
  • To page
    904
  • Abstract
    An approach involving chemical and biological techniques was taken for the detection and quantification of the marine toxin okadaic acid (OA) in mussels from Thermaikos Gulf, Greece, during a 4-month DSP episode that occurred in 2002. Samples were analyzed using the mouse bioassay, high performance liquid chromatography (HPLC) with fluorimetric detection and an enzyme-linked immunosorbent assay (ELISA). Okadaic acid was quantifiable at three different sites of Thermaikos Gulf reaching a maximum concentration of 36 Ag/g hepatopancreas. High correlation was revealed between results derived from HPLC and ELISA (R2=0.998), while 91% consistency between HPLC and the mouse bioassay results was observed.
  • Keywords
    Diarrhetic shellfish poisoning , Mytilus galloprovincialis , okadaic acid , mussels , Mouse bioassay , liquid chromatography , Thermaikos Gulf , ELISA
  • Journal title
    Science of the Total Environment
  • Serial Year
    2006
  • Journal title
    Science of the Total Environment
  • Record number

    985853

    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=985853