عنوان به زبان ديگر :
THE EFFECT OF FOLIC ACID SUPPLEMENTATION IN BETA-THALASSEMIA MAJOR: A RANDOMIZED PLACEBO-CONTROLLED CLINICAL TRIAL
پديد آورندگان :
Mojtahedzadeh Fereidoon نويسنده , Kosaryan Mehrnoush نويسنده , Vaez Mahdavi Mohammad Reza نويسنده , Akbari Jafar نويسنده
چكيده لاتين :
Folic acid is a coenzyme for many important biochemical reactions including synthesis of purines, pyrimidines, and nucleoproteins. The recommended daily allowance of folic acid is 65 - 200 (mu)g/day for infants and children. The recommended dose for deficiency states is 1000 (mu)g/day; the effects of excess amounts of folic acid are unknown. The role of folic acid in preventing progression of arteriosclerosis is rather a new issue. Thrombotic events related to slightly elevated levels of homocystein in adults may be decreased by daily consumption of 1 mg of folic acid together with 5 - 100 mg of pyridoxine.
