شماره ركورد
14658
عنوان به زبان ديگر
FAMILIAL DEFECTIVE APOLIPORROTEIN B 100: FREQUENCY OF R3500Q MUTATION OF APOLIPOROTEIN B GE E IN IRANIAN HYPERCHOLESTEROLEMIC PATIENTS
پديد آورندگان
Mohammadi-Torbati P نويسنده , Khatami S نويسنده , Zeinal S نويسنده , Taghikhani M نويسنده , Allahyari M نويسنده
از صفحه
193
تا صفحه
196
تعداد صفحه
4
چكيده لاتين
Familial defective apolipoprotein (apo) B 100 (FOB) causes early-onset coronary heart
diseases (CHO). It is produced by R3500Q mutation of the apoB gene resulting in decreased binding of
LDL to LDL receptor. We screened the apo B gene for R3500Q mutation in 130 hypercholesterolemic
patients, among whom 30 patients met criteria of familial hypercholesterolemia (FH). The prevalence of
R3500Q allele in this patient population was 0%. To obtain better estimation of mutation frequency, a
broad survey is needed.
شماره مدرك
1198349
لينک به اين مدرک