پديد آورندگان :
Ramezani Amitis نويسنده , Eslamifar Ali نويسنده , Gachkar Latif نويسنده , Pournasir Zahra نويسنده , Banifazl Mohammad نويسنده , Aghakhani Arezoo نويسنده , Rabbani Sayed Mohammad Reza نويسنده , Faghih Mohammad Amin نويسنده , Sardari Soroush نويسنده , Velayati Ali-Akbar نويسنده
چكيده لاتين :
Backgroundand Objective: There have been concerns over possible association between mercury and neurodevelopmental outcomes in infants. In this study we aimed to determine whether blood
levels of mercury are above safe values in Iranian infants or not.
Materials and Methods: A total of 85 infants (0, 2, 4 and 6 months old) were enrolled in this study. All of them received vaccines according to Iranian immunization schedules. We measured total mercury in all blood samples by cold vapor atomic absorption.
Results: The mean concentration of blood mercury in our subjects were as follows: newborns as 33.95 ± 11.86 nmolll (with a range of 23.93-52.84),2 months as 32.94 ± 11.76 nmolll (with a range of 23.92-52.84), 4 months as 30.44 ± 10.44 nmolll (with a range of 23.92-50.85) and 6 months as 37.93 ± 12.97 nmolll (with a range of 21.43-52.34). There was not any significant difference for the mean concentration of blood mercury in those age groups. The lowest level of blood mercury detected was 21.43 nmolll and the highest level was 52.84 nmolli. Conclusion: The finding of this study showed that approximately 33% of the infants had blood mercury levels above the U.S. Environmental Protection Agency recommended reference dose of 5.8 mog/I (29 nmol/I). Therefore, it is needed to reduce exposure ofinfants to mercury from all sources
including thimerosal containing vaccines (TCVs) in Iran.