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Antioxidant, Antibacterial Activities and General Toxicity of Alnus glutinosa, Fraxinus excelsior and Papaver rhoeas

Middleton Patricia نويسنده , Stewart Fiona نويسنده , Al-Qahtani Salem نويسنده , Egan Paula نويسنده , OיRourke Ciara نويسنده , Abdulrahman Aysha نويسنده , Byres Maureen نويسنده , Middleton Moira نويسنده , Kumarasamy Yashodharan نويسنده , Shoeb Mohammad نويسنده , Nahar Lutfun نويسنده , DELAZAR ABBAS نويسنده , Dey Sarker Satyajit نويسنده

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Alnus glut i nosa, Fraxinus excelsior and Papaver rhoeas have long been used in folkloric medicine for the treatment of various ailments. As part of our continuing screening of plant extracts for biological activities, the extracts of A. glu tinosa, F excelsior and P rhoeas have been screened for their antioxidant and antibac terial activit ies, as well as their general toxicity towards brine shrimps. Among the extracts, the methanol (MeOH) extract of F excelsior displayed the highest level of antioxidant activity (RC50= 1.35x 10-2 rng/ml.) and the dichloromethane (DCM) extract of P rhoeas was the most toxic extract towards brine shrimps (LD50=2.4x10-2 mg/ml.). The n-hexane and DCM extracts of F excelsior and the MeOH extract of A. glutinosa were active (MIC values were within 1.25x I0-1 and 1.00 mg/mL) against al l 8 bacterial species tested, including methicillin-resistant Staphylo coccus aureus (MRSA).

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