چكيده لاتين :
Agranulocytosis is a rare but life- Athreatening side effect of thionamides. Some data indicate that the susceptibility
to thionamide-associated agranulocytosis in patients with Gravesי disease has a genetic basis. The case histories of a mother and
her daughter with Gravesי disease who developed agranulocytosis with methimazole are presented here. It seems reasonable to avoid the use
of thionamide derivates in hyperthyroid relatives of patients who have had thionamideinduced agranulocytosis.
