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The Association of Carotid Intima-Media Thickness and Postprandial Dyslipidemia in Patients with Type 2 Diabetes

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This research aimed at investigating the correlation between postprandial dyslipidemia and carotid intimae-media thickness in people with diabetes. Materials and Methods: In 28 diabetic patients and 22 age and sex- matched healthy adults, the carotid intimae-media thickness was measured using Doppler ultrasound. Blood glucose, total cholesterol, triglycerides, LDL and HLD cholesterollevel were measured after overnight fasting and again 4 hours after a standard high-fat meal. Results: The carotid intimae-media thickness of diabetic patients was greater than normal subjects (0.96±0.29 mm vs. 0.7S±0.17 mm, respectively p=0.008). Diabetic patients showed postprandial hypertriglyceridemia (P=0.03). In patients with fasting hyperglycemia and postprandial hypertriglyceridemia, carotid intimae-media thickness was greater than in patients with normal levels (p=O.04and p=0.03 respectively). Conclusion: Postprandial hypertriglyceridemia and fasting hyperglycemia may be an independent risk factor for early atherosclerosis and macrovascular disease in individuals with type 2 diabetes.

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