مرکز منطقه ای اطلاع رساني علوم و فناوري -

چكيده لاتين :

Thyrotoxicosis is often associated with liver and malfunction, often for long durations; sometimes the liver function is substantially impaired for a longer period of time. The exact nature however of the relation between hepatic dysfunction and thyrotoxicosis remains obscure. Presented here is a case report of liver cholestasis as a complication of thyrotoxicosis. Materials and Method: A previously healthy 41year- old man with thyrotoxicosis complicated with liver cholestasis is discussed. Results: The patient reported had a typical thyrotoxicosis but following radioiodine treatment concomitantly developed jaundice and severe pruritus that required several weeks of treatment in hospital and took several months to disappear. In this report the therapeutical considerations as well as the pathogenetic possibilities are reviewed. Conclusion: The association observed is not common but may be severe and should be considered in any case of thyrotoxicosis where a cholestatic condition develops.