چكيده لاتين :
Warfarin induced skin necrosis is a rare complication associated with the use of oral
anticoagulants. Most patients develop this complication at the initiation of therapy. The complication is
usually associated with an underlying thrombophilia. We described a case of 75 year old patient who
developed skin necrosis in her both breasts during warfarin treatment for a deep vein thrombosis.
Thrombophilia screen demonstrated the presence of protein S and antithrombin III deficiency. The
necrotic lesion was excised and defects eventually covered with skin flaps.
