چكيده لاتين :
In this study, the possible involvement of L-type voltage-operated calcium channels in
the vasorelaxant effect of the flavonoid quercetin was investigated, using the isolated aortic
rings from normal male rats. Addition of quercetin (0.1 flM-1 mM) caused a significant
dose-dependent relaxation of noradrenaline (NA)- and KCI-preconstricted rings and
nifedipine attenuated this response, especially for noradrenaline (P(LESS THAN00.05). It is concluded
that the flavonoid quercetin produces a potent relaxation of the rat aorta and blockade of
voltage-operated calcium channels could attenuate this effect.
