پديد آورندگان :
FAZLOLLAHI MOHAMMAD REZA نويسنده , FARHOUDI ABOLHASSAN نويسنده , MOVAHEDI MASOUD نويسنده , GHARAGOZLOU MOHAMMAD نويسنده , MOHAMMADI KOUROSH نويسنده , Rezaei Nima نويسنده
چكيده لاتين :
Chronic Mucocutaneous Candidiasis (CMCC) refers to a group of
immunodeficiencies, characterized by persistent or recurrent infections of the skin,
nails, and mucus membranes caused by candida, A wide range of immunologic
abnormality has been reported in CMCC. Defects in cellular limb of the immune
system, mainly the specific response to antigens of candida species, are well
documented in CMCC patients. A subgroup of patients is predisposed to development
of autoimmune endocrinopathies, These patients need repeated monitoring of
endocrine functions. Immunologic studies are needed to identify the extent of
immunodeficiency and other abnormalities of immune functions. We report three cases
of CMCC. These patients show different phenotypes and highlight the need for
complete evaluation and long term follow-up for accompanying disorders.