عنوان به زبان ديگر :
Antitussive Effect of Plantago lanceolata in Guinea Pigs
پديد آورندگان :
BOSKABADY M. H. نويسنده , RAKHSHANDEH H. نويسنده , AFIAT M. نويسنده , AELAMI Z. نويسنده , AMIRI S. نويسنده
چكيده لاتين :
Background: Several therapeutic effects including antiasthma
and dyspnea have been described for Plantago lanceolata.
In the present study the antitussive effect of this plant
was evaluated.
Methods: The antitussive effects of aerosols of two different
concentrations of Soxhlet and macerated ethanolic extracts,
codeine and saline were tested by counting the number of
coughs produced due to aerosol of citric acid 10 min after exposing
the animal to aerosols of different solutions (n=8 for
each solution).
Results: The results showed significant reductions of cough
number observed in the presence of both concentrations of Soxhlet
and macerated extracts of Plantago lanceolata as compared
to saline treated group (p(LESS THAN)O.OOl). The reduced cough number
observed in the presence of higher concentrations of extracts
was not significantly different from that of lower concentrations
ofLP. Furthermore, there was no significant difference between
the cough numbers observed in the presence of both concentrations
of the extracts with that of codeine.
Conclusion: The ethanolic extracts of Plantago lanceolata
have antitussive effects comparable with that of codeine