چكيده لاتين :
Background: Some types of implants used for orbital implantation
have side effects and complications. In this study we
have evaluated beta-tricalcium phosphate (J3-TCP: ChronOS)
granules as an orbital implant.
Methods: Eighteen rabbits randomly allocated to four groups.
Right eye enucleation performed in groups I to III followed by
filling with autologous bone particles (n=5), a mixture of
autologous bone particles and pure J3-TCP granules (n=5), a
mixture of autologous bone marrow and pure 13-TCP granules
(n=5). Right eye evisceration was done in group IV (n=3), and
then filled with one of the aforementioned materials used in
groups I, II and III. After 12 weeks, exenterated contents were
compared by determining the volumes of the globes, area densitometry
using dual-energy x-ray absorptiometry.
Results: There was no significant difference between the volumes
of enucleated globes before (groups I: 2.6(PLUS-MINUS)O.39, II:
2.6(PLUS-MINUS)O.12 and III: 2.5(PLUS-MINUS)O.3 (ml) and after surgery; (groups I:
2.5(PLUS-MINUS)OA, II: 2.50(PLUS-MINUS)O.2 and III: 2A(PLUS-MINUS)O.3). There was also no significant
differences among the densities of exenterated contents
of all groups; (I: 175(PLUS-MINUS)3, II: 165(PLUS-MINUS)1 and III: 174(PLUS-MINUS)3
mg/cm"), In all enucleated groups, histopathologic evaluations
showed remarkable vascularization and fibrous ingrowth
which were remarkable in eviscerated group. No significant
complication was observed.
Conclusion: J3-TCP granules offer good cosmetic results with low
risk of infection and extrusion. However, further studies are required
before they can be used in human as a new orbital implant.
